his post will be based in Karen Liu’s lab in the Centre for Craniofacial and Regenerative Biology (CCRB) at King’s College London. The overall theme of CCRB is to investigate the mechanisms that control head development and repair, underpinning a broader understanding of the genetic basis of craniofacial malformations and disease. Research is multidisciplinary using different experimental models and techniques to explore cell signalling, transcriptional networks and cell behaviour during development and disease. Another focus is studying the in vivo function and biology of stem cells in different craniofacial organs as well as their potential uses for clinical therapies involving the enhancement of natural repair processes and regenerative approaches.

 

The department has over 60 research staff and major funding from the Medical Research Council, Biotechnology and Biomedical Science Research Council, ARC, Wellcome Trust and European Union. All the groups occupy newly refurbished laboratories and core facilities on floor 27 of Guy’s Tower. 

This is a 3-year fixed-term, full-time Research Assistant position funded by a BBSRC research grant. The post holder will work within Karen Liu’s Lab in the Centre for Craniofacial and Regenerative Biology at King’s College London, working jointly with Matthias Krause’s Lab at the Randall Centre for Cell and Molecular Biophysics, King’s College London.

 

The overall aim of the project is to investigate how the actin cytoskeleton regulates the trafficking and activity of Wnt receptor complexes, combining molecular, cellular and imaging approaches to uncover new mechanisms that control the duration and strength of the Wnt response. 

 

The Research Assistant will work closely with PhD students and postdocs within the Liu and Krause labs, attending regular joint meetings. Key desired experience includes experience with animal models, ideally Xenopus frogs or mouse. Required skills included experience with molecular cloning, genome editing, protein biochemistry, microscopy, tissue culture and database maintenance. Engagement with research aims may lead to co-authorship. Additional training and career development opportunities for Research Assistants will be strongly encouraged.

 
 

This is a full time (37.5 hours per week), and you will be offered a fixed term contract for 3yrs. 

 

Research staff at King’s are entitled to at least 10 days per year (pro-rata) for professional development. This entitlement, from the Concordat to Support the Career Development of Researchers, applies to Postdocs, Research Assistants, Research and Teaching Technicians, Teaching Fellows and AEP equivalent up to and including grade 7. Visit the Centre for Research Staff Development for more information.